Glomerulotubular balance, tubuloglomerular feedback, and salt homeostasis.
نویسندگان
چکیده
The homeostasis of NaCl is critical to complex organisms with closed blood systems. Kidneys regulate this salt excretion by modulating the rapport between glomeruli and tubules. The tubules respond to glomeruli with glomerulotubular balance, whereas glomeruli respond to tubules through tubuloglomerular feedback. These relationships are dynamic, mysterious, and amenable to mathematical analyses. The biology underlining what is known about these interactions is observational, fragmentary, and somewhat inconclusive. Discussed here is a simple tethering of these interrelated concepts.
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عنوان ژورنال:
- Journal of the American Society of Nephrology : JASN
دوره 19 12 شماره
صفحات -
تاریخ انتشار 2008